Weight Loss Drugs Like Zepbound Could Help Treat Arthritis, Trial Shows

Eli Lilly's Breakthrough in Treating Arthritis: Zepbound Showcased as Potential Game-Changer

A recent clinical trial has revealed that a weight loss drug, Zepbound (tirzepatide), can be an effective add-on treatment for psoriatic arthritis. The results, released by Eli Lilly on Friday, demonstrate the potential of an integrated treatment approach to improve the standard of care in treating this chronic condition.

The TOGETHER-PsA trial involved 271 people with active psoriatic arthritis who were overweight or obese. Half received ixekizumab (Taltz), while the other half received Taltz plus Zepbound. By week 36, patients taking the combination therapy experienced a significantly greater reduction in arthritis symptoms - a 64% relative improvement compared to those taking Taltz alone.

Moreover, patients on the combination therapy also witnessed substantial weight loss, with about 10% of participants experiencing at least this amount by week 36, far surpassing the 0.8% seen in the Taltz-only group.

Mark Genovese, senior vice president of Lilly Immunology development, hailed the results as a "comprehensive way" to improve care for patients with psoriatic arthritis. Meanwhile, Joseph Merola, chair of dermatology and professor of rheumatology at the University of Texas Southwestern, stated that PsA appears to be an obesity-related condition, emphasizing the potential benefits of addressing weight in conjunction with treatment.

The discovery has significant implications for the future of treating psoriasis and psoriatic arthritis. GLP-1 drugs have already revolutionized obesity treatment, with tirzepatide outperforming semaglutide in clinical trials. Eli Lilly's expansion of Zepbound's approval to obstructive sleep apnea is a testament to its growing potential.

However, the findings must undergo peer review and regulatory scrutiny before they can be widely adopted. Nevertheless, the research holds promise for transforming treatment regimens for patients with psoriasis and psoriatic arthritis.

omg this is like super exciting news ! I mean, who doesn't want to see people living better lives without all the joint pain and whatnot? it's amazing that they found a combo therapy that actually works and the weight loss part? game changer . I'm also loving that it's being seen as an obesity-related condition - like, let's talk about getting people moving and healthy! . of course, we gotta wait for peer review and all that jazz, but a girl can dream

Just what we need more meds that only help weight loss , psoriasis and arthritis are super annoying conditions already! But I guess it's kinda awesome that this new combo therapy is showing promising results ... 64% relative improvement? That's a big deal, but also think about the side effects with meds like Zepbound - don't wanna be one of those people stuck on some crazy diet and med routine

Just saw this crazy news about Zepbound and I'm like YAAAS ! Can you believe a weight loss drug is now being used to treat arthritis? It's mind-blowing how researchers are finding new ways to tackle chronic conditions . The fact that patients taking the combination therapy experienced a 64% reduction in symptoms is HUGE, and I'm so here for any treatment that can help people manage their psoriasis and psoriatic arthritis better . Also, addressing weight loss as part of treatment makes total sense, considering PsA is kinda linked to obesity . Fingers crossed this discovery leads to more game-changing treatments in the future #Zepbound #ArthritisTreatment #PsoriasisSupport #WeightLossMatters

I'm not sure about this Zepbound thing... it sounds like just another drug to weigh us down . I mean, what's next? A pill that fixes our sleep schedule too? I don't think so. We need to take a step back and think about the bigger picture here - is this just another way for Big Pharma to rake in cash, or is it actually helping people? The results are promising, I'll give them that, but we need more than just a fancy clinical trial to convince me .

OMG I'm literally super hyped about this Zepbound breakthrough!! The fact that it's reducing arthritis symptoms by 64% is insane and the weight loss stats are straight fire , especially considering how hard it can be to lose weight in the first place. I've been following Eli Lilly's updates on this drug for ages, and it's amazing to see it finally showing promise . The link between psA and obesity is so important to acknowledge , and it's great that they're exploring ways to address that in treatment. Fingers crossed these results hold up after peer review !

This is just like when I was in college, we thought semaglutide was the bee's knees for weight loss lol . Now this Zepbound thingy is showing up all over the place! I'm not surprised though, GLP-1 drugs have been getting a lot of love lately . It makes sense that addressing obesity would be key to treating psoriasis and arthritis, those conditions are like two peas in a pod, right? I mean, who doesn't love a good weight loss story? But for real, the fact that this is a breakthrough for a whole new class of treatments is pretty exciting. Now we just need to get it through all the hoops before we can start seeing more patients benefit from it .

This breakthrough in treating Arthritis is a perfect example of how multiple approaches can lead to better outcomes! We're not just talking about throwing another pill at a problem, but actually tackling the root causes - like weight loss in this case . It's all about finding that balance between treatment and lifestyle changes. So often we focus on just one aspect of health, when really it's the culmination of many factors that makes all the difference . And let's not forget the power of community - if patients are working together to support each other's wellness journeys, we can achieve even more . The key takeaway here is that integrated care and a holistic approach can lead to real game-changers in our lives.

OMG u guys this 1st clinical trial 4 Zepbound as add-on therapy 4 PsA is MIND BLOWING!! 64% rel reduction in arthritis symptoms & substantial weight loss too?! Tirzepatide is already a game-changer for obesity treatment, but adding it 2 existing therapies could be a total game-changer. Eli Lilly's on the right track here! The fact that PsA is linked 2 obesity now makes sense - we need 2 address this comorbidity in treatment. Can't wait 2 see these findings get peer reviewed & go mainstream

I'm intrigued by this new development, but how reliable are these results? I mean, a 64% relative improvement in just 36 weeks sounds too good to be true . What's the actual data behind that number? Have they considered other factors like side effects or long-term consequences? Not to mention, Tirzepatide is still an obesity drug - how does this relate to psoriatic arthritis? Can we trust the claims from Eli Lilly and their collaborators without more evidence?

I gotta say, this Zepbound breakthrough is looking pretty promising! The fact that it's not just improving symptoms but also helping with weight loss is a huge win . And what's crazy is that the researchers are already seeing how obesity can exacerbate psoriasis and psoriatic arthritis - like, it makes total sense now that we know this drug can tackle both issues at once . Of course, more testing is needed, but I'm keeping my fingers crossed for a game-changing treatment . Can't wait to see where this takes us!

omg this is so exciting! Zepbound is like, literally a game-changer for people suffering from arthritis! I mean, 64% relative improvement in just 36 weeks? that's crazy fast progress! And weight loss too - 10% of participants lost at least that much weight? it's amazing to think about how this could help alleviate not just pain but also some of the other symptoms associated with obesity. I'm so glad Eli Lilly is pushing forward with research like this, and hopefully we'll see more breakthroughs in the future!

I'm kinda surprised that more ppl aren't already on tirzepatide (Zepbound) for psoriatic arthritis... like, it's been out there for a while now . The fact that adding Zepbound to existing treatments like Taltz results in such significant improvements is def promising. I think this could be the start of more integrated treatment approaches that focus on weight management and overall health . Not saying it's gonna change everything overnight, but it's definitely a step in the right direction.

Just read about Zepbound and I'm so stoked! This tirzepatide thingy could be a total game-changer for people with psoriatic arthritis. 64% improvement in symptoms? That's like, whoa! And substantial weight loss too? That's a major plus. I'm all about integrated treatment approaches now. It's like, we've been treating psoriasis and arthritis separately for years, but maybe it's time to think outside the box (or pill). GLP-1 drugs are already killing it in obesity treatment, so why not give Zepbound a shot?

This is so exciting ! I've been following this trial and it's amazing to see Zepbound show such potential in treating psoriatic arthritis. The fact that it can also lead to significant weight loss is a game-changer - it's not just about managing symptoms, but also addressing the root cause of the condition. I'm loving how researchers are thinking outside the box and exploring new ways to treat this chronic condition. It'll be interesting to see how this plays out in clinical practice and what other breakthroughs we can expect from Eli Lilly.

I don’t usually comment but I gotta say, this news about Zepbound is straight fire ! A weight loss drug that also reduces arthritis symptoms? That's like a match made in heaven . I've been following the treatment of psoriatic arthritis for friends and family members, and it's always a tough road to recovery. This breakthrough has me hopeful for people who are struggling with the condition .

And let's be real, weight loss is often overlooked when treating chronic conditions like this. It's not just about taking meds, it's about addressing the root cause of the problem . I'm excited to see Eli Lilly push forward with Zepbound and potentially change the game for patients with psoriasis and psoriatic arthritis .

But, gotta give props to Dr. Merola's point about PsA being an obesity-related condition . It's time we start recognizing that weight loss is a crucial part of managing this condition . I'm all ears for more updates on Zepbound and its potential to transform treatment regimens !