New Study Suggests Moderate Link Between Lithium Exposure and Autism Risk, But Experts Caution Against Drawing Direct Conclusions.
A new study published in the journal JAMA Pediatrics has found a modest association between exposure to tap water with higher levels of lithium during pregnancy and an increased risk of autism spectrum disorder (ASD) in children. According to the research, pregnant women who lived in areas with higher concentrations of lithium in drinking water had a slightly elevated risk of having a child diagnosed with ASD.
The study's findings suggest that children born to mothers exposed to tap water with higher levels of lithium during pregnancy were more likely to receive an ASD diagnosis compared to those whose mothers drank water with lower lithium levels. Specifically, the researchers found that children whose mothers consumed water with higher lithium levels had a 24% to 26% increased risk of ASD diagnosis, while those exposed to the highest levels had a 46% greater risk.
However, experts are cautioning against drawing direct conclusions between lithium exposure and ASD due to the limited scope of the study. According to Dr. Beate Ritz, co-author of the study, further research is needed to establish a causal link between lithium exposure and autism diagnosis. "Any drinking water contaminants that may affect the developing human brain deserve intense scrutiny," she said in a statement.
While previous studies have suggested potential connections between environmental exposures, such as pesticides, air pollution, and phthalates, and ASD risk, none of them point to these factors as direct causes of the disorder. Other researchers have noted that it's challenging to pinpoint causality when studying environmental factors, especially considering factors like socioeconomic status and population demographics.
Dr. Max Wiznitzer, director of the Rainbow Autism Center at University Hospitals Rainbow Babies and Children's Hospital in Cleveland, emphasized the need for more research on lithium exposure and its potential impact on fetal development. "It's an interesting association, but causation is definitely not proven," he said. "We have to see if there's a viable and biologically plausible mechanism by which a small amount of lithium in the water supply can somehow do this."
Ultimately, the implications of the study's findings for public health policy remain unclear, as they are linked with potential benefits associated with lithium exposure, such as lower rates of hospitalization for psychiatric disorders and suicide.
A new study published in the journal JAMA Pediatrics has found a modest association between exposure to tap water with higher levels of lithium during pregnancy and an increased risk of autism spectrum disorder (ASD) in children. According to the research, pregnant women who lived in areas with higher concentrations of lithium in drinking water had a slightly elevated risk of having a child diagnosed with ASD.
The study's findings suggest that children born to mothers exposed to tap water with higher levels of lithium during pregnancy were more likely to receive an ASD diagnosis compared to those whose mothers drank water with lower lithium levels. Specifically, the researchers found that children whose mothers consumed water with higher lithium levels had a 24% to 26% increased risk of ASD diagnosis, while those exposed to the highest levels had a 46% greater risk.
However, experts are cautioning against drawing direct conclusions between lithium exposure and ASD due to the limited scope of the study. According to Dr. Beate Ritz, co-author of the study, further research is needed to establish a causal link between lithium exposure and autism diagnosis. "Any drinking water contaminants that may affect the developing human brain deserve intense scrutiny," she said in a statement.
While previous studies have suggested potential connections between environmental exposures, such as pesticides, air pollution, and phthalates, and ASD risk, none of them point to these factors as direct causes of the disorder. Other researchers have noted that it's challenging to pinpoint causality when studying environmental factors, especially considering factors like socioeconomic status and population demographics.
Dr. Max Wiznitzer, director of the Rainbow Autism Center at University Hospitals Rainbow Babies and Children's Hospital in Cleveland, emphasized the need for more research on lithium exposure and its potential impact on fetal development. "It's an interesting association, but causation is definitely not proven," he said. "We have to see if there's a viable and biologically plausible mechanism by which a small amount of lithium in the water supply can somehow do this."
Ultimately, the implications of the study's findings for public health policy remain unclear, as they are linked with potential benefits associated with lithium exposure, such as lower rates of hospitalization for psychiatric disorders and suicide.